Anaplasma phagocytophilum Encephalitis: A Case Report and Literature Review of Neurologic Manifestations of Anaplasmosis

Anaplasma phagocytophilum is an obligate intracellular, Gram-negative pathogen, causative agent of Human Granulocytic Anaplasmosis (HGA). HGA usually manifests as a non-specific febrile illness, accompanied by evidence leucopenia, thrombocytopenia, and alteration in liver enzymes. Neurologic manifestations anaplasmosis are rare rarely reported. We describe 62-year-old man who developed encephalitis due to infection. The patient favorably responded intravenous doxycycline recovered without neurological sequela. In the tick endemic area, clinicians should have high index suspicion for tick-borne diseases patients presenting with deficits. A prompt diagnosis treatment lead improvements morbidity mortality.